Contact Information
Entomology & Plant Pathology
Mississippi State University
Mississippi State, MS 39762-9775
TEL: (662) 325-2085
FAX: (662) 325-8837
Building Locations
People :: Faculty
Shien Lu
Assistant Professor of Plant Pathology
Department of Entomology and Plant Pathology
Mississippi State University
Mississippi State MS 39762-9655
Tel: (662) 325-3511
Fax: (662) 325-8955
Email: slu@plantpath.msstate.edu
Education:
Ph.D., Plant Pathology, Washington State University
M.S., Plant Pathology, Shandong Agricultural University, China, PR.
B.S., Plant Protection, Shandong Agricultural University, China, PR.
Research Interest:
My research interest is in molecular biology of plant-associated bacteria, focusing on plant pathogenesis and development of bacterium-based approaches of plant disease management. The research in my laboratory involves: (1) identification of rhizobacteria antagonistic to plant soilborne pathogens; (2) characterization of the genes dedicated to bacterial antagonism; and (3) development of novel antifungal agents by reprogramming nonribosomal peptide synthetases. Ultimately, these antagonistic bacteria and genetic materials could be used to manage plant diseases.
Teaching:
I currently teach three courses: Introductory Plant Pathology, Plant Disease Management, and Plant Bacteriology.
Selected Publications:
Lu, S.-E., J. Novak, F. W. Austin, G. Gu, D. Ellis, M. Kirk, S. Wilson-Stanford, M. Tonelli, and J. L. Smith. 2009. Occidiofungin, a unique antifungal glycopeptide produced by Burkholderia contaminans strain MS14. Biochemistry (in press).
Gu, G., N. Wang, N. Cahney, L. Smith, and S.-E. Lu*. 2009. AmbR1 is a key transcriptional regulator for antifungal activity of Burkholderia contaminans strain MS14. FEMS Microbiology Letter. 297:54-60.
Sagaram, U. S., DeAngelis K. M., Trivedi P., Andersen G. L., Lu S.-E., N. Wang. 2009. Bacterial diversity analysis of huanglongbing pathogen-infected citrus, using phylochip arrays and 16S rRNA gene clone library sequencing. Applied and Environmental Microbiology 75: 1566-1574.
Ingram, D. M. and S.-E., Lu. 2009. Evaluation of bacteriophage for the management of bacterial canker in greenhouse tomatoes. Plant Health Progress. doi:10.1094/PHP-2009-0512-01-RS.
Gu, G., L. Smith, N. Wang, H. Wang, and S.-E. Lu.* 2009. Biosynthesis of an antifungal oligopeptide in Burkholderia contaminans strain MS14. Biochemical and Biophysical Research Communications. 380: 328-332.
Fullone, M. R., A., Paiardini, D. C., Gross, S.-E., Lu, A., Fiore and I. Grgurina. 2007. Mutational analysis and homology modelling of SyrC, the aminoacyltransferase in the biosynthesis of syringomycin. Biochemical and Biophysical Research Communications 364: 201-207.
Lu, S.-E., A. R. A. Henn, and D. H. Nagel. 2007. First report of ear soft rot of corn Zea mays) caused by Burkholderia gladioli in the United States of America. Plant Disease (disease note). 97: 1514.
Wang N., S.-E. Lu, A. R. Records, and D. C. Gross. 2006. Characterization of the transcriptional activators SalA and SyrF, which are required for syringomycin and syringopeptin production by Pseudomonas syringae pv. syringae. Journal of Bacteriology. 188 (9):3290-8.
Wang N., S.-E. Lu, J. Wang, Z. J. Chen, and D. C. Gross. 2006. The expression of genes encoding lipodepsipeptide phytotoxins by Pseudomonas syringae pv. syringae is coordinated in response to plant signal molecules. Molecular Plant-Microbe Interactions 19 (3):257-69.
Wang N., S.-E. Lu, Q. Yang, S.-H. Sze, and D. C. Gross. 2006 Identification of the syr-syp box in the promoter regions of genes dedicated to syringomycin and syringopeptin production by Pseudomonas syringae pv. syringae B301D. Journal of Bacteriology. 188 (1):160-8.
Lu, S.-E., N. Wang, J.-L. Wang, J. Z. Chen and D. C. Gross. 2005. Oligonucleotide microarray analysis of the salA gene regulon in Pseudomonas syringae pv. syringae. Molecular Plant-Microbe Interactions. 18:324-333.
Lu, S.-E., J. D. Sole, and D. C. Gross. 2003. Characterization of the argA gene required for arginine biosynthesis and syringomycin production by Pseudomonas syringae pv. syringae. Applied and Environmental Microbiology 69:7273-7280.
Lu, S.-E., B. K. Scholz-Schroeder, and D. C. Gross. 2002. Construction of pMEKm12, an expression vector for protein production in Pseudomonas syringae. FEMS Microbiology Letters. 210:115-121.
Lu, S.-E., B. K. Scholz-Schroeder, and D. C. Gross. 2002. Characterization of the salA, syrF, and syrG regulatory genes located at the right border of the syringomycin gene cluster of Pseudomonas syringae pv. syringae. Molecular Plant-Microbe Interactions. 15:43-53.
Scholz-Schroeder, B. K., J. D. Soule, S.-E. Lu, I. Grgurina, and D. C. Gross. 2001. A physical map of the syringomycin and syringopeptin gene clusters localized to an approximately 145-kb DNA region of Pseudomonas syringae pv. syringae strain B301D. Molecular Plant-Microbe Interactions. 14:1426-1435.
Guo, X.-Q, S.-E. Lu, C.-X. Zhou, Y.-Z. Song, X.-B. Meng, C.-C. Zheng, and F.-J. Wen. 2001. RNA-mediated viral resistance against potato virus Y in transgenic tobacco plants. Acta Phytopathologica Sinica. 31:349-356.