Natraj Krishnan

Natraj Krishnan

Associate Professor
Graduate Coordinator

Insect Physiology

Mailing Address:
Box 9775
Mississippi State, MS 39762
Research Areas:
  • Insect-Plant Interactions
  • Oxidative stress and regulation of antioxidant response in insect digestion
  • Endocrine and circadian control of response to oxidative stress
  • Circadian regulation of cellular homeostasis

Courses Taught:
  • BCH 1011 - First Year Seminar - Natures Timepiece (offered in Fall)
  • BCH 4113/6113 - Essentials of Molecular Genetics (offered Summer 10 week, online)
  • BCH 4414/6414 - Protein Methods (offered in Fall)
  • BCH 4623/6623 - Biochem Spec Tissues/Medical Biochem (offered in Spring)
  • EPP 4333/6333 - Principles of Insect Anatomy and Physiology (offered in Spring online)
  • EPP 8343 - Advances in Insect Anatomy - Structure and Function (offered in Fall, even years)
  • EPP 8353 - Advances in Insect Physiology and Biochemistry (offered in Fall, odd years)

Society Membership:
  • Entomological Society of America
  • Society for Integrative and Comparative Biology


  • Catchot, B. D., F. R. Musser, J. Gore, N. Krishnan, D. R. Cook, S. D. Stewart, G. M. Lorenz, S. Brown, N. Seiter, A. L. Catchot, D. L. Kerns, R. Jackson, K. S. Knighten. 2021. Sublethal impacts of novaluron on tarnished plant bug (Hemiptera: Miridae) adults. Journal of Economic Entomology 114(2):739-746. Download
  • Hearst, S, A. Bednářová., B. Draughn., K. Johnson, D. Mills, C. Thomas, J. Scales., E. T. Keenan., J. V. Welcher, N. Krishnan. 2021. Expression of Drosophila matrix metalloproteinases in cultured cell lines alters neural and glial cell morphology. Frontiers in Cell and Developmental Biology 9:1242.  Download
  • Bednářová, A., M. Kropf, N. Krishnan. 2020. The surfactant polyethoxylated tallowamine (POEA) reduces lifespan and inhibits fecundity in Drosophila melanogaster- In vivo and in vitro study. Ecotoxicology and Environmental Safety 188:109883.  Download
  • Catchot, B., C. J. Anderson, J. Gore, R. Jackson, K. Rakshit, F. Musser, N. Krishnan. 2020. Novaluron prevents oogenesis and oviposition by inducing ultrastructural changes in ovarian tissue of young adult Lygus lineolaris. Pest Management Science.  Download
  • Chaudhuri, A., R. Johnson, K. Rakshit, A. Bednářová, K. Lackey, S.S. Chakraborty, N. Krishnan, A.Chaudhuri. 2020. Exposure to Spectracide® causes behavioral deficits in Drosophila melanogaster: Insights from locomotor analysis and molecular modeling. Chemosphere. 248:126037.  Download
  • Yue, Z., N. Krishnan, T. M. Tseng. 2020. Antifeedant effect of sicklepod extract on soybean looper Chrysodeixis includens (Lepidoptera: Noctuidae). Mississippi Academy of Sciences Journal 65(3): 293-300.
  • Bednářová, A., A. Tomčala, M. Mochanová, D. Kodrik, N. Krishnan. 2018. Disruption of adipokinetic hormone medicated energy homeostasis has subtle effects on physiology, behavior and lipid status during aging in drosophila. Frontiers in Physiology 9:949 Download
  • Bednářová, A., D. Kodrik, A. Chaudhuri, N. Krishnan. 2018. Neuroendocrine regulation of homeostasis in insects: Implications for metabolic disorders in humans. Advances in Health and Disease 3:1-45.
  • Formby, J. P., J. C. Rodgers, F. H. Koch, N. Krishnan, D. A. Duerr, J. J. Riggins. 2018. Cold tolerance strategy and invasive potential of the redbay ambrosia beetle (Xyleborus glabratus) in the eastern United States. Biological Invasions 20:995-1007. Download
  • Bednářová, A., M. E. Hanna, K. Rakshit, J. M. O'Donnell, N. Krishnan. 2017. Disruption of dopamine homeostasis has sexually dimorphic effects on senescence characteristics of Drosophila melanogaster. The European Journal of Neuroscience 45(6):816-825. Download
  • Bednářová, A., M. Hanna, I. Durham, T. VanCleave, A. England, A. Chaudhuri, N. Krishnan. 2017. Lost in translation: Defects in transfer RNA modifications and neurological disorders. Frontiers in Molecular Neuroscience 10:135. Download
  • Fleming, D. E., N. Krishnan, F. Musser 2017. Polygalacturonase gene expression and enzymatic activity in salivary glands of laboratory reared and wild populations of Lygus lineolaris (Hemiptera: Miridae). European Journal of Entomology 114:16-24. Download
  • Adams, A., J. Gore, A. L. Catchot, F. Musser, D. R. Cook, N. Krishnan, J. T. Irby. 2016. Residual and systemic efficacy of chlorantraniliprole and flubendiamide against corn earworm (Lepidoptera: Noctuidae) in soybean. Journal of Economic Entomology 109(6):2411-2417. Download
  • Adams, A., J. Gore, A. L. Catchot, F. Musser, D. R. Cook, N. Krishnan, J. T. Irby. 2016. Susceptibility of Helicoverpa zea (Lepidoptera: Noctuidae) neonates to diamide insecticides in the Midsouthern and Southeastern United States. Journal of Economic Entomology 109(3):1161-1166. Download
  • Fleming, D. E., N. Krishnan, A. L. Catchot, F. R. Musser. 2016. Susceptibility to insecticides and activities of glutathion S-transferase and esterase in populations of Lygus lineolaris (Hemiptera:Miridae) in Mississippi. Pest Management Science 72(8):1595-1603. Download
  • Giejdasz, K., M. Fliszkiewicz, A. Bednarova, N. Krishnan. 2016. Reproductive potential and nesting effects of Osmia rufa (syn. bicornis) female (Hymenoptera: Megachilidae). Journal of Apicultural Science 60(1). Download
  • Krishnan, N., K. Giejdasz, M. Fliszkiewicz, A. Bednarova. 2016. Reproductive potential and nesting effects of Osmia rufa (syn. bicornis) female (Hymenoptera: Megachilidae). Journal of Apicultural Science 60(1):75-86. Download
  • Bednářová, A., D. Kodrik, N. Krishnan. 2015. Knockdown of adipokinetic hormone synthesis increases susceptibility to oxidative stress in Drosophila—a role for dFoxO? Comparative Biochemistry and Physiology - Part C: Toxicology & Pharmacology 171:8-14. Download
  • Hanna, M., E., A. Bednarova, K. Rakshit, A. Chaudhuri, J. M. O'Donnell, N. Krishnan. 2015. Perturbations in dopamine synthesis lead to discrete physiological effects and impact oxidative stress response in Drosophila. Journal of Insect Physiology 73:11-19. Download
  • Kodrik, D., A. Bednarova, M. Zemanova, N. Krishnan. 2015. Hormonal regulation of response to oxidative stress in insects-an update. International Journal of Molecular Sciences 16(10):25788-25816. Download
  • Wasielewski, O., T. Wojciechowicz, K. Giejdasz, N. Krishnan. 2015. Enhanced UV-B radiation during pupal stage reduce body mass and fat content, while increasing deformities, mortality and cell death in female adults of solitary bee Osmia bicornis. Insect Science 22(4):512-520. Download
  • Bednářová, A., D. Kodrik, N. Krishnan. 2013. Adipokinetic hormone exerts its antioxidative effects using a conserved signal-transduction mechanism involving both PKC and cAMP by mobilizing extra- and intracellular Ca2+ stores. Comparative Biochemistry and Physiology, 158(3):142-149. Download
  • Bednářová, A., D. Kodrik, N. Krishnan. 2013. Unique roles of glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects. Comparative Biochemistry and Physiology, 164(1):91-100. Download
  • Bednářová, A., N. Krishnan, I.C. Cheng, J. Vecera, H.J. Lee, D. Kodrik. 2013. Adipokinetic hormone counteracts oxidative stress elicited in insects by hydrogen peroxide: in vivo and in vitro study. Physiological Entomology, 38:54-62. Download
  • Ivanchenko, M.G., D. den Os, G.B. Monhausen, A. Bednarova, N. Krishnan. 2013. Auxin increases the hydrogen peroxide (h2o2) concentration in tomato (Solanum lycopersicum) root tips while inhibiting root growth. Annals of Botany, 112(6):1107-1116. Download
  • Vinokurov, K., A. Bednarova, A. Tomcala, T. Staskova, N. Krishnan, D. Kodrik. 2013. Role of adipokinetic hormone in stimulation of salivary gland activities: the fire bug Pyrrhocoris apterus L. (Heteroptera) as a model species. Journal of Insect Physiology. Download
  • Wasielewski, O., T. Wojciechowicz, K. Giejdasz, N. Krishnan. 2013. Overwintering strategies in the red mason solitary bee - physiological correlates of midgut metabolic activity and turnover of nutrient reserves in females of Osmia bicornis. Apidologie. Download
  • Fliszkiewicz, M., K. Giejdasz, O. Wasielewski, N. Krishnan. 2012. Influence of winter temperature and simulated climate change on body mass and fat body depletion during diapause in adults of the solitary bee, Osmia rufa (Hymenoptera: Megachilidae). Environmental Entomology 41(6):1621-1630. Download
  • Krishnan, N., D. Kodrik. 2012. Endocrine control of oxidative stress in insects. Pages 261-270 in Farooqui and Farooqui, editors, Molecular Aspects of Oxidative Stress in Cell Signaling in Vertebrates and Invertebrates. Wiley-Blackwell Publishers. Download
  • Krishnan, N., K. Rakshit, E.S. Chow, J.S. Wentzell, D. Kretzshmar, J.M. Giebultowicz. 2012. Loss of circadian clock accelerates aging in neurodegeneration-prone mutants. Neurobiology of Disease 45(3):1129-1135. Download
  • Meermeier, N.,N. Krishnan. 2012. Circadian regulation of cellular homeostasis-implications for cell metabolism and clinical diseases. Medical Hypotheses 79(1):17-24. Download
  • Rakshit, K., N. Krishnan, E.M. Guzik, E. Pyza, J.M. Giebultowicz. 2012. Effects of aging on the molecular circadian oscillations in Drosophila. Chronobiology International 29(1):5-14. Download
  • Rakshit, K., N. Krishnan. 2012. Orchestration of oxidative stress responses in Drosophila melanogaster: A promoter analysis study of circadian regulatory motifs. Pages 327-335 in Faroqui and Farooqui, editors, Molecular Aspects of Oxidative Stress in Cell Signaling in Vertebrates and Invertebrates. Wiley-Blackwell Publishers.
  • Veoera, J., N. Krishnan, A. Mithofer, H. Vogel, D. Kodrik. 2012. Adipokinetic hormone-induced antioxidant response in Spodoptera littoralis. Comparative Biochemistry and Physiology 155(2):389-395. Download
  • Wasielewski, O., T. Wojciechowicz, K. Giejdasz, and N. Krishnan. 2011. Influence of methoprene and temperature on diapause termination in adult females of the over-wintering solitary bee, Osmia rufa L. Journal of Insect Physiology 57(12):1682-1688. Download